师资队伍
  • 教师简介
  • 双少敏
  • 发布时间2013-05-09 0:00:00 来源: 编辑者: 点击量:

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    双少敏,女,1965年生,教授,博士生导师。新世纪学术技术带头人333人才工程省级人选,山西省高等学校青年学术带头人和中青年拔尖创新人才,山西省委联系的高级专家,兼任山西省化学会理事,亚太环糊精化学国际委员会委员,《分析化学》编委,国家自然科学基金委评审专家,山西省政协委员,山西省青联委员,九三学社山西省委委员,九三学社山西大学委员会主任委员。曾赴日本大阪大学、加拿大多伦多大学、麦克马斯特大学、香港浸会大学等高访研究。多年来从事分析化学研究,主要研究方向为超分子化学、化学与生物传感、生化分析。
    教育经历:
    1982.9-1986.7山西大学化学化工学院分析化学专业本科
    1986.9-1989.7山西大学化学化工学院分析化学硕士
    1995.9-1998.7华南理工大学化学与生物工程学院分析化学博士
    工作经历:
    1989.9-2001.7 山西大学化学化工学院任教
    1999.9-2001.7 香港浸会大学化学系博士后研究
    2001.9-至今山西大学化学化工学院教授
    2003年,与香港浸会大学签订科技合作和共同培养研究生协议。
    2004年,加拿大多伦多大学高访。
    2007年,日本大阪大学合作交流。
    20086月至9月,日本大阪大学应用化学系进行合作研究。
    200910月至20104月,加拿大麦克马斯特大学进行合作研究。
    讲授课程
    本科生:《化学英语》、《高等分析化学》、《化学前沿》
    研究生:《分析生物化学(英文版)》、《超分子化学》
    科研方向:
    1. 超分子化学 2. 化学与生物传感器 3. 生化分析
    科研项目:
    主持在研项目如下:
    2009.1-2011.12山西省自然科学基金:(No.2009011012-1
    新型纳米超分子主体的研制及分子识别作用研究               8
    2009.1-2011.12 国家自然科学基金重大研究计划项目:
    新型细胞钙荧光探针的合成及钙信号转导作用 (No.90813018 )    50
    2012.1-2015.12国家自然科学基金:
    超分子主体功能化的磁性纳米复合物的制备及包合性能研究(2117508760
    已结题项目如下:
    2008.07-2010.07山西省回国留学人员科研项目
    新型甲烷化学传感器研究及分析应用    200820                     6
    2006.01-2009.12 国家自然科学基金重点项目:
    化学修饰光纤瓦斯传感器及化学热力学预警基础研究 (No.50534100)    160
    2007.01-2009.12山西省高校优秀创新团队资助项目:可降解环保油墨色料研究       50
    2007.06-2008.12太原市科技攻关计划:太原市科技明星专项:
    模式滤光检测瓦斯的新型化学传感器的研究 (No.07020406)    10
    2006.5-2008.12    山西省国际科技合作计划项目:基于溶解氧型传感器的研制和开 10
    2006.01-2008.12国家自然科学基金:
    新型杯芳烃发光受体的合成及其分子识别性能研究 (No. 20575038)     30
    2003.7   山西省自然科学基金:

    构筑新型超分子受体及其分子识别功能研究     资助额:6万元,
    2001-10  
    国家自然科学基金:

    环糊精探针型主体分子的合成及其与靶分子DNA作用研究  资助额:22万元
    2002-3     教育部资助优秀年轻教师基金:
    环糊精荧光探针的研制及其与DNA作用的研究  资助额:10万元
    2001-11              山西省高校科技开发项目:
    新型药物载体材料的研制    资助额:3万元
    2000-12                  山西省回国留学人员科研项目:
    新型电荷型超分子的研制及其应用   资助额:2万元

    2004-11     专项科研:青年学术带头人   资助额:10万元,
    2003-12   
    山西省回国留学基金:

    环糊精超分子组装及其与DNA作用研究    资助额:4.5万元,
    发表代表性论文:

    1.         Li, Ruijin; Yuan, Chao; Dong, Chuan; Shuang, Shaomin; Choi, Martin M. F.In vivo antioxidative effect of isoquercitrin on cadmium-induced oxidative damage to mouse liver and kidney .Naunyn-Schmiedeberg's Archives of Pharmacology.2011,383(5).437-445
    2.         Wei, Yanli; Ren, Yanfang; Li, Jun; Shuang, Shaomin; Dong, Chuan. Characterization of room temperature phosphorescence of propranolol and the chiral discrimination between R- and S-isomers.Analyst (Cambridge, United Kingdom) (2011), 136(2), 299-303. 
    3.         Zhongping Li, Xu Wang, Guangming Wen, Shaomin Shuang, Chuan Dong, Man Chin Paau, Martin M.F. Choi, Application of hydrophobic palladium nanoparticles for the development of electrochemical glucose biosensor, Biosensors and Bioelectronics 26 (2011) 4619-4623.
    4.         Wenjuan Dong, Chuan Dong, Shaomin Shuang, Martin M.F. Choi, Near-infrared luminescence quenching method for the detection of phenolic compounds using N-acetyl-l-cysteine-protected gold nanoparticlestyrosinase hybrid material, Biosensors and Bioelectronics, 2010, (25) 10431048.
    5.         Suozhu Wu, Wenping Cheng, Yan Qiu, Zhongping Li, Shaomin Shuang, Chuan Dong. Fiber Optic pH Sensor Based on Mode-Filtered Light Detection. Sensors & Actuators: B, 2010, 144(1): 255-259.
    6.         Zhongping Li, Jie Gao, Xiaoting Xing, Suozhu Wu, Shaomin Shuang, Chuan Dong, Man Chin Paau, Martin M. F. Choi*, Synthesis and Characterization of n-Alkylamine-Stabilized Palladium Nanoparticles for Electrochemical Oxidation of Methane,J. Phys. Chem. C, 2010, 114: 723–733.
    7.         Yanli wei, sufang wang shaomin shuang, Chuan Dong,Chiral discrimination between d- and l-tryptophan based on the alteration of the fluorescence lifetimes by the chiral additives ,Talanta 2010, 81: 4-5):1800 - 1805
    8.         Jin-Ping Song, Yu-Jing Guo*, Shao-Min Shuang, Chuan Dong, Study on the inclusion interaction of ethyl violet with cyclodextrins by MWNTs/Nafion modified glassy carbon electrode, J. Incl. Phenom. Macrocycle Chem., 201068467-473.
    9.         Jin-Ping Song, Yu-Jing Guo, Qiang Zhao, Shao-Min Shuang, Chuan Dong, Martin M.F. Choi, Assemblies of brilliant cresyl violet to DNA in the presence of γ-cyclodextrin, Talanta 82 (2010) 681-686.
    10.     Shao-min Shuang, Xiao-na Qiao,Dan-dan Wang,Li Fan,Dong-tao Lu,Li-xiao Mu, Ye-hong Zhou.Analytical Behavior of Fura-2 and Its Determination of [Ca2+]i in Lymphocytes Treated with Cefotaxime. Journal of Measurement Science and Instrumentation.Vol.1 NO.4,Dec,2010, 395-400
    12.     Shengmei Song, Dong Ju, Junfen Li, Duxin Li, Yanli Wei, Chuan Dong, Peihua Lin, Shaomin Shuang, Synthesis and spectral characteristics of two novel intramolecular charge transfer fluorescent dyes. Talanta, 2009, 77(5): 1707-1714.
    13.     Junfen Li, Shaomin Shuang, Chuan Dong, Study on the phosphorescence characterizations of palmatine chloride on the solid substrate and its interaction with ctDNA. Talanta, 2009, 77(3): 1043-1049.
    14.     Yan Zhang, Shaomin Shuang, Chuan Dong, Chung Keung Lo, Man Chin Paau, Martin M. F. Choi, Application of HPLC and MALDI-TOF MS for Studying As-Synthesized Ligand–Protected Gold Nanoclusters Products, Analytical Chemistry, 2009, 81(4): 1676-1695.
    15.     Sheng-mei Song, Xiao-li Hou, Yan-bo Wu, Shao-min Shuang, Cheng Yang, Yoshihisa Inouec and Chuan Dong, Study on the interaction between methyl blue and human serum albumin by fluorescence spectrometry. Journal of Luminescence. 2009, 129 (3): 169-175
    16.     Wenting An, Yong Jiao, Chuan Dong, Cheng Yang, Yoshihisa Inoue, Shaomin Shuang.Spectroscopic and molecular modeling of the binding of meso-tetrakis(4-hydroxyphenyl)porphyrin to human serum albumin. Dyes and Pigments, 2009, 81(1): 1-9.
    17.     Guomei Zhang, Dujuan Gao, Jianbin Chao, Shaomin Shuang, Chuan Dong. The interaction of C.I. Basic Red 5 with complementary negatively charged hosts: 4-Sulfonatocalix[4]arene and carboxymethyl-β-cyclodextrin, Dyes and Pigments, 2009, 82( 1): 40-46.
    18.     Caihong Zhang, Weili Shen, Ruying Fan, Guomei Zhang, Lingzhi Shangguan, Jianbin Chao, Shaomin Shuang, Chuan Dong, Martin M.F. Choi,Study of the contact charge transfer behavior between cryptophanes (A and E) and fullerene by absorption, fluorescence and 1HNMR spectroscopy, Analytica Chimica Acta, 2009,650 :118123.
    19.     Wen Ting An, Yong Jiao, Xiao Hua Sun, Xiao Ling Zhang, Chuan Dong, Shao Min Shuang, Ping Fang Xia, Man ShingWong. Synthesis and binding properties of carboxylphenyl-modified calix[4]arenes and cytochrome c. Talanta, 2009,79: 54-61.
    20.      Zhongping Li, Yong Guo, Suozhu Wu, Shaomin Shuang, Chuan Dong, Junfen Li, Xu Wu, Shaomin Shuang, Chuan Dong, Martin M.F. Choi. Methane sensor based on nanocomposite of palladium/multi-walled carbon nanotubes grafted with 1,6-hexanediamine. Sensors & Actuators: B,2009, 139(2):.453-459.
    21.      Jie Qiao, Shengnan Tang, Yanni Tian, Shaomin Shuang, Chuan Dong, Martin M.F. Choi. Electro-catalytic oxidation of methane at multi-walled carbon nanotubes-Nafion/nickel hydroxide modified nickel electrode. Sensors & Actuators: B, 2009, 138 (2): 402-407.
    22.     Jin-Ping Song, Yu-Jing Guo, Shao-Min Shuang, Chuan Dong. Electrochemical behavior of brilliant cresyl violet at multi-wall carbon nanotubes/Nafion modified glassy carbon electrode and its interaction with cyclodextrins. Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2009, 64: 115-120.
    23.     Yunlong Wang, Xiaona Qiao, Wenchao Li, Yehong Zhou, Yong Jiao, Cheng Yang, Chuan Dong, Yoshihisa Inoue, Shaomin Shuang. Study on the Complexation of Isoquercitrin with b-Cyclodextrin and Its Derivatives by Spectroscopy. Analytica Chimica Acta, 2009, 650(1):124-130.
    24.     Guomei Zhang, Yinghui Li, Shaomin Shuang, Chuan Dong, Martin M.F.Choi, WinghongChan. Development application of a fluorescent for potassium ions based on a calix[6]arene ionophore and anovel cationic dye. Supramolecular Chemistry. 2009, 1-8.
    25.    Caihong Zhang, Weili Shen, Guangming Wen, Jianbin Chao, Liping Qin, Shaomin Shuang, Chuan Dong, Maitin M.F. Choi, Spectral Study on the Interaction of Cryptophane-A and Neutral Molecules, Talanta, 2008, 76(2). 235-240.
    26.    Jun Li, YanliWei, Limin Guo, Caihong Zhang, Yong Jiao, Shaomin Shuang, Chuan Dong Study on pectroscopic characterization of Cu porphyrin/Co porphyrin and their interactions with ctDNA, Talanta, 2008, 76(1), 34-39.
    27.    Wenye Li, Hui Li, Guomei Zhang, Jianbin Chao, Lixia Ling, Shaomin Shuang, Chuan Dong, Interaction of water-soluble calix[4]arene with l-tryptophan studied by fluorescence spectroscopy, Journal of Photochemistry and Photobiology A: Chemistry, 2008, 197(2-3), 389-393.
    28.    Guangming Wen, Jun Zheng, Chungui Zhao, Shaomin Shuang, Chuan Dong, Martin M.F. Choi, A microbial biosensing system for monitoring methane, Enzyme and Microbial Technology, 2008, 43(3), 257-261.
    29.    Haiyan Wang, Albert W.M. Lee, Shaomin Shuang*, Martin M.F. Choi, SPE/HPLC/UV studies on acrylamide in deep-fried flour-based indigenous Chinese foods, Microchemical Journal, 2008, 89: 90-97.
    30.    Yan Chang, Jie Qiao, Qiaoling Liu, Lingzhi ShangGuan, Xuwen Ma, Shaomin Shuang, Chuan Dong, Electrochemical Behavior of Hydrogen Peroxide at a Glassy Carbon Electrode Modified with Nickel Hydroxide-decorated Multi-walled Carbon Nanotubes, Analytical Letters, 2008, 41(17): 3147-3160.
    31.     Gao Dujuan, Zhang Guomei, Bai Juli, Zhao Chungui, Shuang Shaomin, Dong Chuan Identification of methane-consuming bacteria by intrinsic fluorescence spectra, Luminescence, 2008, 23(2),69-70.
    32.     Li Zhongping, Ma Xuwen; Shuang Shaomin, Dong Chuan, Kinetic spectrophotometric method determination of sulphite based on its additional reaction with pararosaniline, Luminescence, 2008, 23(2),81-82.
    33.      Qiao Jie, Dong Ruifen, Li Duxin, Shuang Shaomin, Dong Chuan, Determination of azithromycin by capillary electrophoresis with electrochemiluminescence (CE-ECL) detection, Luminescence, 2008, 23(2),88-89.
    34.     Shen Weili, Zhang Caihong, Fan Ruying, Dong Chuan, Shuang Shaomin, Fluorescence spectral study on the inclusion complex of cryptophane-E and CHCl3, Luminescence, 2008, 23(2), 92-93.
    35.     Song Shengmei; Hou Xiaoli; Shuang Shaomin, Dong Chuan, Study on the interaction between methyl blue and HSA in the presence of beta-CD-HP-beta-CD by molecular spectroscopy, Luminescence, 2008, 23(2),92-93.
    36.     Guangming Wen, Yan Zhang, Shaomin Shuang, Chuan Dong, Martin M. F. Choi, Application of a biosensor for monitoring of ethanol, Biosensors & Bioelectronics, 2007, 23(1), 121-129.
    37.     Xiaohua Sun, Wenye Li, Pingfang Xia, Haibin Luo, Yingli Wei, Man Shing Wong, Yuen-Kit Cheng, Shaomin Shuang, Phenyl-calix[4]arene-based fluorescent sensors: Cooperative binding for carboxylates, Journal of Organic Chemistry,2007, 72(7), 2419-2426.
    38.     Xiaoli Hou, Xiaofei Tong, Wenjuan Dong, Chuan Dong, Shaoming Shuang, Synchronous fluorescence determination of human serum albumin with methyl blue as a fluorescence probe, Spectrochimica Acta, Part A: Molecular and Biomolecular Spectroscopy, 2007, 66 A (3), 552-556.
    39.     Yan Zhang, Guangming Wen, Yehong Zhou, Shaomin Shuang, Chuan Dong, Martin M. F. Choi, Development and analytical application of an uric acid biosensor using an uricase-immobilized eggshell membrane, Biosensors & Bioelectronics, 2007, 22(8), 1791-1797.
    40.     Yanli Wei, Chuan Dong, Diansheng Liu, Shaomin Shuang, Carmen W. Huie, Enantioselective Quenching of Room-Temperature Phosphorescence Lifetimes of Proteins: Bovine and Human Serum Albumins,  Biomacromolecules, 2007, 8(3), 761-764.
    41.    Yehong Zhou, Guomei Zhang, Zhongru Wang, Haiyan Wang, Chuan Dong, Shaoming Shuang, The Interaction of Piroxicam with Neutral (HP-β-CD) and Anionically Charged (SBE-β-CD) β-cyclodextrin, Journal of Inclusion Phenomena and Macrocyclic Chemistry, 2006, 56(1-2), 215-220.
    42.    Limin Guo, Wenjuan Dong, Xiaofei Tong, Chuan Dong, Shaoming Shuang, Study on spectroscopic characterization of Pd porphyrin and its interaction with ctDNA, Talanta, 2006, 70(3), 630-636.
    43.    Guomei Zhang, Diansheng Liu, Shaomin Shuang, Martin M. F. Choi, A homocysteine biosensor with eggshell membrane as an enzyme immobilization platform, Sensors and Actuators, B: Chemical, 2006, B 114(2), 936-942.
    44.    Man Shing Wong, Pingfang Xia, Pik Kwan Lo, Xiao Hua Sun, Wai Yeung Wong, Shaoming Shuang, Synthesis of Oligophenylene-Substituted Calix[4]crown-4's and Their Silver(I) Ion-Induced Nanocones Formation, Journal of Organic Chemistry, 2006, 71(3), 940-946.
    45.    Yanli Wei, Jianqing Li, Chuan Dong, Shaomin Shuang, Diansheng Liu, Carmen W. Huie, Investigation of the association behaviors between biliverdin and bovine serum albumin by fluorescence spectroscopy, Talanta, 2006, 70(2), 377-382.
    46.     Yingli Wei, Xiliang Guo, Shaomin Shuang, Chuan Dong, Xiaohua Sun, Manshing Wong, Self-assembly of meso-tetrakis(4-N-ethylpyridiniurmyl) porphyrin and tetracarboxyl-phenyl calix[4]arene, Journal of Photochemistry and Photobiology, B: Biology, 2005, 81(3), 190-194.
    47.     Junfen Li, Jianqing Li, Shaomin Shuang, Chuan Dong, Study of the luminescence behavior of seven quinolones on a paper substrate, Analytica Chimica Acta, 2005, 548(1-2), 134-142.
    48.     Xiliang Guo, Wenting An, Shaomin Shuang, Fangqin Cheng, Chuan Dong, Study on spectroscopic characterization of meso-tetrakis (4-hydroxyphenyl) porphyrin (THPP) in β-cyclodextrin and its derivatives, Journal of Photochemistry and Photobiology, A: Chemistry, 2005, 173(3), 258-263.
    50.     Baoli Wu, Guomei Zhang, Yan Zhang, Shaomin Shuang, Martin M. F. Choi, Measurement of glucose concentrations in human plasma using a glucose biosensor, Analytical Biochemistry, 2005, 340(1), 181-183.
    51.     Man Shing Wong, Pingfang Xia, Xiaoling Zhang, Pik Kwan Lo, Yuen-Kit Cheng, Kai-Tai Yeung, Xiliang Guo, Shaoming Shuang, Facile Synthesis of Oligophenylene-Substituted Calix[4]arenes and Their Enhanced Binding Properties, Journal of Organic Chemistry, 2005, 70(7), 2816-2819.
    52.     Yanli Wei, Shaomin Shuang, Chuan Dong, Weijun Jin, Chunguang Gao, Yansheng Wei, Changsong Liu, Recent development on room temperature phosphorescence, Trends in Applied Spectroscopy, 2004, 5, 195-224.
    53.     Xiliang Guo, Shaomin Shuang, Xiaoping Wang, Chuan Dong, Jinghao Pan, Hassan Y Aboul-Enein, Comparative study on the inclusion behaviour of cyclodextrin derivatives with venoruton and rutin by thin layer chromatography, Biomedical Chromatography, 2004, 18(8), 559-563.
    54.     Baoli Wu, Guomei Zhang, Shaomin Shuang, Martin M. F. Choi, Biosensors for determination of glucose with glucose oxidase immobilized on an eggshell membrane, Talanta, 2004, 64(2), 546-553.
    55.     Martin M. F. Choi, Shaomin Shuang, H. Y. Lai, S. C. Cheng, Rebecca C. W. Cheng, Bohr K. B. Cheung, Albert W. M. Lee, Gas chromatography-mass spectrometric determination of total isothiocyanates in Chinese medicinal herbs, Analytica Chimica Acta, 2004, 516(1-2), 155-163.
    著作:
    1.       墨水化学原理及应用,董川,温建辉,双少敏,张国梅,2007,科学出版社,ISBN 978-7-03-020080-8
    2.       环保色料与应用,董川,双少敏,卫艳丽, 2009, 化学工业出版社, ISBN 978-7-122-04278-1
    3.       煤矿瓦斯监测新技术, 董川,双少敏,李忠平, 2010-5,化学工业出版社
    4.       译著:隐色体化学,董川,双少敏等,化学工业出版社,2010
    相关成果:
    获奖情况:
    2010年,入选山西省高等学校中青年拔尖创新人才
    2009年,被聘为《分析化学》第十二届编委会委员;
    2008年,被评为山西省新世纪学术技术带头人333人才;获山西省科学技术二等奖(项目名称:生物大分子探针的分析研究及应用 )
    2007年,获第五届山西省青年科技奖并获得青年科研专家称号;获山西省教科文卫体系统知识女性创新成果奖;获山西省教科文卫体系统杰出知识女性荣誉称号;获山西省三八红旗手荣誉称号,并记一等功一次;
    2006年,被评为山西大学精神文明建设文明个人
    2005年,获国家技术发明二等奖;(项目名称:新型光敏水解褪色材料的研究及应用)九三学社建社60周年优秀社员称号;
    2004年,山西省科学技术二等奖;(项目名称:分子组装构筑环糊精超分子体系);山西省高等学校科技进步理论一等奖(项目名称:分子组装构筑环糊精超分子体系);被评为山西省高等学校青年学术带头人;第五届中国发明展览会金奖;
    2003年、2002年,获山西省优秀硕士论文指导教师奖两次;所授课程被评为山西大学优师优课奖两次;
    2002年,获得山西大学富士康优秀教师奖;入选国家教育部优秀青年教师资助计划;被授予全国文明家庭称号;
    2000年,获山西省科技进步理论二等奖(项目名称:环糊精超分子的研究)。
     
    专利情况
    项目名称                          专利号ZL          批准日           专利证号
    1一种B-胡萝卜素包合物及其制备方法   200510012829.4      2007.05.23.       326475
    2一种无尘板书写液及其擦剂        200610048142.0       2009.12-09          576954
    3一种AB反应显色墨水及其配套笔  200610048141.6       2008.05.07          395416
    4一种划粉及其制作方法            200610048396.2       2008.05.07.         395497
    5一种亚硫酸钠的稳定剂           200610048316.3       2008.10.01.          431846
    6一种可褪色划粉及其制备方法      200610048324.8       2008-11-12          442428
    7一种红色书写液专利类型         200610012760.x       2008-11-12          442283
    8一种两用笔                     200720101214.3       2008.06.04          1059655
    9一种目视检测电镀铬溶液中三价铬200710061736.x       2009.12.09           577727
    的方法及其装置
    10一种复合膜修饰镍电极的制备方法  200710139430.1     2010-01-13          590380
    11一种黄色荧光墨水及其擦除液    200710061867. 8       2010-05-19          620742
    12异槲皮苷β-环糊精及衍生物    200810055353.6    2008-07-04          637435
         包合物和其制备方法.
    13一种固体荧光画笔              200810079842.5       2010-08-25           665273
    14一种固体彩色书写笔           200810079651.9       2010-06-02           630205
    15可变多色面泥粉及其制备方法    200810054423.6      2010-01-13           562583
    16异槲皮苷包合物及其制备方法    200810055353.6       2010-06-09           637435
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